The most common use of Astrion® is in anti-aging and cosmetic (skin health, nails, hair, etc) supplements. Astrion® has been clinically studied and proven in human trials to improve overall skin health.

In a recent 2025 study, Astrion® was studied for its effects as both a cosmetic ingredient and as a functional supplement. This was a randomized, double-blind, placebo-controlled clinical trial that included 150 healthy adults. These adults were then split into four different groups: Astrion® supplementation using topical cream, Astrion® supplementation using oral capsule, Astrion® supplementation using a combination of topical cream and oral capsule and a placebo group.

The results of the study concluded that the test groups showed a significant increase in skin collagen, brightness and moisture with a decrease in melanin, number of visible pores and texture in the skin.

Topical Cream Only:

• Collagen increase by 8.7%
• Elasticity improved by 6.5%
• Visible pore count reduced by 10.6%

Oral Capsules Only:

• Skin texture improved by 18.5%
• Collagen increased by 13.2%
• Melanin reduced by 6.3%

Combination:

• Collagen increased by 13.7%
• Visible pore count reduced by 28.5%
• Moisture retention improved by 12.9%
• Elasticity improved by 9%
• Melanin reduced by 8.2%
• Brightness increased by 4.2%
• Skin texture improved by 19.8%

Collagen is beneficial for skin as it is one of the most important structural proteins in the body, specifically in skin. Collage plays a key role in skin firmness, elasticity, hydration and youthfulness. Both type I and type III collagen are found I the skin. Your body’s ability to produce collagen decreases as you age. Astrion® was shown to improve collagen.

Melanin can be both good thing and a bad thing. While Melanin can help protect against UV radiation, neutralizes free radicals and can aid in preserving eye and brain health, excess melanin can have negative consequences. Having too much Melanin can lead to dark patches on the skin (i.e age spots). Astrion® was shown to decrease melanin.

Pores are necessary for regulating body temperature (ie sweat) and keeping the skin moisturized, but an abnormal number of visible pores (specifically hair follicle pores) can lead to increased acne and blackheads, poor skin texture and skin quality.  Astrion® was shown to decrease the number of visible pores.

Astrion® is a combination of both Astragalus and Centella. The combo provides both Astragalosides (from Astragalus), as well as Asiaticosides from Centella. Both of which have a variety of benefits.

Centella has been shown in-vitro to increase dermal fibroblasts. Dermal fibroblasts are cells which are responsible for generating connective tissue. Centella has quite some backing as a way to aid with wound healing and is beneficial at increasing the production of collagen.

As for the Astragalus, it is a source of Astragalosides, which has a variety of benefits in the body. Astragalus has been shown to help with Hyaluronic Acid and collagen production, both of which are very important for hydration and elasticity of the skin.  Hyaluronic Acid is a substance that your body produces, and it has thick/fluid like consistency. It is found predominantly in the skin, as well as the joints. It is responsible for keeping your skin and joints hydrated.

As a final takeaway, supplementing with Astrion® increases collagen and hyaluronic acid in human skill cells while simultaneously reduces melanin and pores.