Infinis Nutrition Sleep: Deep Rem Sleep Achieved

We have said this numerous times, Infinis Nutrition doesn’t go mediocre on any of their formulas. And that extends to the new Sleep supplement. This is a 20 serving tub of 1 scoop(12.5g) per serving.

GABA Triple Release Blend – 1,030mg

GABA is the most popular relaxation ingredients in the industry. It is known as an inhibitory neurotransmitter in and helps to regulate 1) depressive and 2) sedative actions; this means GABA plays a significant role in deep sleep and relaxation. While it is widely documented as to how GABA acts in the body, there is little literature supporting these claims in regards to oral supplementation at least. This is due to the fact that in order for the benefits of GABA to take effect, it first must cross the blood-brain barrier, which is no easy feat by any means. In regard to oral supplementation, more human trials would certainly be beneficial. PharmaGABA is a branded form of GABA that is marketed as a dietary supplement to support relaxation and stress management. Unlike synthetic GABA, PharmaGABA is a natural form of GABA produced through fermentation by Lactobacillus hilgardii, a specific strain of bacteria. Lastly, GABA probiotics combine the benefits of GABA (gamma-aminobutyric acid) with probiotics, aiming to support both mental and digestive health. The idea is that the probiotic strains used in these supplements can support gut health, which in turn may positively impact brain health and mood due to the gut-brain axis.

Zylaria – 500mg

Onw of NuLiv Science’s ingredients featured here is Zylaria, this supports both 1) sleep and 2) mood by promoting GABA levels in the brain. As mentioned above, GABA is known as an inhibitory neurotransmitter; a neurotransmitter that blocks chemical messages from being passed along. Fun fact, GABA is actually the most present inhibitory neurotransmitter in the adult human brain and plays a substantial role in sleep and relaxation. Zylaria’s mechanism of action is rather unique, and it acts in several different ways:

1. Reduces GABA-T, an enzyme that breaks down GABA to glutamate. This helps to increase GABA levels within the brain.
2. Increases GAD activity; a neurotransmitter that plays a crucial role in balancing chemicals in the brain, specifically GABA.
3. Increases Brain Derived Neurotrophic Factor, or BDNF. Low levels of BDNF are linked to poor sleep quality and depression in adult subjects.

To make it clear as can be, Zylaria increases GABA levels, prevents the breakdown of GABA, and increases BDNF. All three of these mechanisms have a wide range of benefits including enhanced mood, relaxation, deep sleep, sleep quality, and brain function. Overall, it is a great ingredient to include in a deep sleep/relaxation formula.

DailyZz – 485mg

DailyZz is a dietary supplement designed to promote restful sleep and relaxation. It typically combines several ingredients that are known to support sleep quality and reduce stress. You get improved sleep quality by combining ingredients that promote relaxation and regulate sleep, DailyZz aims to enhance sleep quality and help you fall asleep more easily. Reduced stress and anxiety with ingredients like GABA and L-theanine can help reduce stress and anxiety, which may contribute to better sleep. Also has support for sleep patterns. Melatonin and herbal extracts can support a more natural sleep cycle and improve overall sleep consistency.

Levagen+ – 300mg

Levagen+ is a branded supplement that features a specific form of palmitoylethanolamide (PEA), a naturally occurring fatty acid amide found in various foods and the human body. PEA is known for its potential anti-inflammatory, analgesic, and neuroprotective properties. Research suggests that PEA might help with conditions related to chronic pain, inflammation, and neurodegenerative diseases. It’s thought to work by reducing inflammation and supporting nerve health using around 300 mg to 1,200 mg per day. 

Lactium – 300mg

Lactium is a proprietary ingredient derived from milk protein hydrolysate, specifically designed to help manage stress and support relaxation. It contains a bioactive peptide called casein phosphopeptides (CPP), which has been shown to have calming effects. Lactium is often used to help reduce symptoms of stress and anxiety. It may be beneficial for individuals experiencing chronic stress or situational anxiety. By promoting relaxation, Lactium can potentially improve sleep quality, especially when stress is a contributing factor to sleep disturbances. By managing stress and promoting relaxation, Lactium can support overall emotional and mental well-being. Typical Dosage: Lactium is generally taken in doses ranging from 150 mg to 300 mg per day. 

Sensoril- 250mg 

Ashawaganda has recently undergone an increase in popularity within the supplement industry, and for good reason. It’s known as an adaptogenic herb and has been used in ancient Ayurveda medicine for centuries due to its anxiety and stress reducing properties. Ashawaganda is rich in many bioactive compounds; its benefits are often attributed to its rich withanolide content; compounds that have a variety of benefits including antioxidative, anti-inflammatory, and hormone balancing properties.

Ashawaganda reduces our stress hormone cortisol. Chronic increase in cortisol levels has been linked to a number of negative health parameters; by reducing our stress hormone cortisol, it will help to promote overall health and well-being. Because of its cortisol-reducing properties, there is substantial evidence to support the fact that Ashawaganda may improve time to fall asleep and sleep quality in subjects with and without insomnia.

Phytocann BP – 220mg

Phytocann BP is a specific formulation that combines phytocannabinoids with black pepper extract. This combination aims to enhance the absorption and effectiveness of phytocannabinoids, such as cannabidiol (CBD), through the use of black pepper’s active compounds. The addition of black pepper extract (piperine) to phytocannabinoid supplements like Phytocann BP is intended to improve the bioavailability of cannabinoids. Phytocannabinoids, particularly CBD, are known for their potential to reduce anxiety and stress. Phytocannabinoids may also help manage pain and inflammation while supporting overall well-being through improved absorption and effectiveness of the active compounds. Dosage recommendations can vary based on the specific formulation and concentration of phytocannabinoids and black pepper extract. 

Sleeproot Valerian Root Extract – 200mg

Valerian Root Extract has been used for centuries as a natural remedy for promotion relaxation. Valerian Root Extract has sedation properties making it a good choice for a sleep aid. Valerian Root Extract may help increase levels of GABA which promotes a deeper state of relaxation and sleep. 

Dosages can be up to 600mg prior to bed time. The 200mg dosage does fall within the acceptable range.

L-Theanine – 200mg

Theanine is known as the “feel good” ingredient. Theanine can cause the body to relax without causing drowsiness. L-Theanine works by increasing the levels of neurotransmitters such as GABA, dopamine, and serotonin. As previously mentioned, by increasing these levels it can promote a deeper state of sleep. Theanine can help regulate mood, stress and and anxiety. The dosage of 200mg is sufficient for our purposes here. 

Apigemin- 100mg

Apigemin is a dietary supplement that combines various plant-based compounds, including apigenin, a naturally occurring flavonoid. Apigenin is found in a variety of fruits, vegetables, and herbs, such as chamomile, parsley, and celery. Apigenin is known for its potential calming effects, which may help in reducing symptoms of anxiety and stress. It interacts with the central nervous system to promote relaxation. Due to its calming properties, apigenin may also support better sleep quality and help with issues related to insomnia or poor sleep. The dosage of apigenin in supplements like Apigemin can vary depending on the formulation and intended use. Common dosages range from 10 mg to 50 mg per day.

Venetron Rafuma – 50mg

Venetron Rafuma is a specific formulation of a supplement that incorporates Venetron, which is a patented extract derived from the Rafuma plant (Raphanus sativus), commonly known as radish. This ingredient is used for its potential benefits related to stress management and mood support. Venetron is thought to work by modulating neurotransmitter levels and supporting the body’s stress response. It may help in managing the effects of chronic stress and promoting emotional well-being. Venetron may help the body adapt to stress and improve resilience to stressors. This can lead to reduced feelings of anxiety and improved overall stress management. By supporting neurotransmitter function and reducing stress, Venetron Rafuma may help stabilize mood and contribute to a more balanced emotional state. Dosage can vary based on the specific product formulation. Common dosages might range from 100 mg to 300 mg per day.

Saffron Extract – 10mg

Saffron Extract has several benefits for overall brain health. Some research suggests that saffron may help improve mood and reduce symptoms of depression by modulating neurotransmitter levels, such as serotonin and dopamine, in the brain.

Research suggests that saffron may have cognitive-enhancing effects and could potentially improve memory recall, learning ability, and overall cognitive performance.

Saffron extract may influence the levels of certain neurotransmitters in the brain, such as serotonin and gamma-aminobutyric acid (GABA), which play key roles in mood regulation, stress response, and cognitive function.

Melatonin Double Release Blend – 3mg

Melatonin Double Release Blend is a specialized formulation of melatonin designed to offer a sustained release of the hormone throughout the night. Melatonin is a naturally occurring hormone produced by the pineal gland that helps regulate the sleep-wake cycle. The “Double Release” concept typically involves a dual-release mechanism to support both sleep onset and maintenance throughout the night. The immediate-release component helps with falling asleep more quickly. The extended-release mechanism supports a more consistent sleep through the night, helping to reduce the likelihood of waking up during the night. By providing this steady level of melatonin throughout the night, this formulation can help prevent disturbances in sleep continuity. Common dosages range from 1 mg to 5 mg of melatonin.