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Chromax®: Uses, Side Effects, Interactions, Dosage and Supplements

By November 23, 2020May 2nd, 2022No Comments


Chromax is a highly bioavailable patented form of Chromium Picolinate from Nutrition21. Chromax has been clinically shown to aid in weight management, body composition, appetite control, cognitive health, glucose metabolism, insulin function and energy support in over 35 human clinical trials.

Uses of Chromax®

Chromax® is currently used in over 80 consumer brands, most notably for its weight management and body composition benefits. Within the sports nutrition industry, brands are utilizing Chromax® for its confirmed weight management benefits in fat burning supplements.

An ingredient is only as good as its bioavailability. Research has shown that Chromax® is up to 15x more bioavailable than other forms of Chromium such as chromium chloride or chromium polynicotinate.  This has been found by examining both uptake into tissues and urinary excretion.

Chromax Superior Absorption

The real benefit of Chromax® occurs after it is absorbed. Chromax® works by promoting optimal insulin function.  Insulin is released by the body to allow glucose in the blood to enter cells, providing them with the energy to function. By promoting optimal insulin function, Chromax® can help promote healthy blood sugar levels, more efficient carbohydrate metabolism, reduced caloric intake and improved muscle maintenance during weight loss.

Chromax® can help support weight loss through its ability to impact body composition when used as part of a healthy diet and exercise program.  In a 72-day trial, users who supplemented with 200mcg of Chromax® led to improvements in lean body mass gain and fat loss compared to placebo.

Chromax Body Composition

Chromax® can also help with appetite control and suppression. In an 8-week trial, users who supplemented with 600mcg showed a 1.8x reduction in appetite and more than 2x the reduction in carbohydrate cravings compared to the placebo group.

Chromax Cravings

Chromax® has also been shown to be more effective in maintaining lean body mass during weight loss than many popular diet programs alone.  A study looked at Chromax® supplementation combined with calorie restriction compared to popular diet programs like low carb, low fat, high protein, high fiber, and extremely low-calorie diets. The results showed that combining calorie restriction with Chromax® led to more fat loss and less muscle loss compared to these other popular diets.

Chromax vs. Diets

While Chromax® is popular for its role in weight management, a secondary benefit is mood elevation. Studies have shown that individuals suffering from depression experienced positive mood change when supplementing with Chromium.

With the benefits of weight management, body composition, appetite control and mood elevation, it is no surprise we see more and more brands using Chromax® in their products.

Formulations with Chromax®

Chromax® is a non-stimulant ingredient that can work as a stand-alone single ingredient, or as part of a larger formula promoting healthy weight management, body composition, appetite control, and mood elevation, because of its ease of use and low dose when used as part of a healthy diet and exercise program.

Side Effects of Chromax®

No side effects are known at this time.

Recommended Chromax® Dosage

Results can be seen with Chromax® at 200mcg, but it can be used as high as 1000mcg safely per clinical studies.

Recommended Supplements Featuring Chromax®

The following products contain Chromax®, and are recommended supplements for Fitness Informant:


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