The 5 Best Nootropic Supplements In 2025: Our Tested Reviews

Apollon Nutrition is a powerhouse when it comes to formulas, and Universal Solider is a perfect example of their commitment to launching products that are always good enough to infest our ranking guides. Universal Soldier is a nootropic supplement that 

It starts off with 3g of Tyrosine, which helps with dopamine production, and is then followed by Acetyl-L-Carnitine. ALCAR is our favorite form of Carnitine, as it crosses the blood-brain barrier, and is really the only Carnitine you can “feel”.To please the gamers, they have also included a clinical dose of NooLVL, which is an ingredient that has clinical studies showing it to be beneficial for gamers. At 1.6g, it is at the clinical dose. 

Apollon has thrown in Lion’s Mane, which is a mushroom that is common in Nootropic supplements. It may aid with NGF levels, which support brain health. Another common ingredient found in Universal Soldier is Alpha GPC. Alpha GPC is a source of Choline, which converts to Acetylcholine in the brain. At 600mg is a solid dose.

Now come two botanicals, called Rhodiola and Bacopa. Bacopa can work as an Acetylcholinesterase inhibitor, and Rhodiola is a common ingredient used for its adaptogenic effects. Both are dosed at 300mg, which is good! Now comes Uridine, which promotes synthesis of brain phosphatidylcholine and helps to support cholinergic function. At 250mg, users are getting a sufficient dosage.

Now comes Grape Seed extract, which is an antioxidant that is usually used for blood flow, and has some antioxidant properties. Of course we have everyone's favorite energy booster Caffeine… along with its friends Di-Caffeine Malate, and Coffeeberry. You get a mix of fast-acting and slow-acting Caffeine, so you will have sustained energy levels and no crash. 

Now comes KannaEase, which can provide a calming/relaxing feeling. This goes well for gamers under stressful situations. Following this, you have AstraGin, which may help with absorption of several ingredients in Universal Soldier. 

Finally, Universal Soldier contains Huperzine A, which is a commonly used Acetylcholinesterase inhibitor. At 200mcg, you are getting a strong dose.

Overall, Universal Soldier is a versatile and powerful supplement, ideal for gamers, students, or even as a pre-workout. Whether you're looking to enhance focus during gaming, stay sharp for schoolwork, or boost energy for your workout, Universal Soldier stands out as a top-tier option for cognitive support and sustained energy.

Who Makes It?

Apollon Nutrition is a hardcore supplement line that isn't afraid to go places other brands haven't. Not only are they hardcore, they know how to make great products and care about providing clinical doses of ingredients. Certainly not a brand for beginners, however seasoned veterans and supplement nerds will certainly be impressed with what they do.

You can always count on Morphogen to make a solid product, and they are a go-to for our ranking guides. Cognigen makes this list, as it is simply a great nootropic supplement to have around. 

The profile starts off with 3g of Tyrosine. Tyrosine is a precursor to dopamine, and you typically want it at 1-2g. Well here you get 3g, which is a strong dose. Following this comes D-Serine, which can reduce anxiety, improve attention, and help with information retention. At 1g, you are getting a solid dose. 

We really like how this is not a “crack-you-out” nootropic. RhodioPrime is an energy enhancer, however it is not a stimulant. It is a popular adaptogen, as it has a 6% standardization. That is double the amount you typically find on the market. They have added TeaCrine, which is structurally similar to Caffeine, however does not hit you the same way. It provides long-lasting energy, and won’t give you any jitters, and there is no comedown. Speaking of Caffeine, you also get zum-XR, which is an extended-release form of Caffeine. You get 100mg of Caffeine, which is about a cup's worth of coffee, and this does not hit you all at once, so you have longer lasting energy. 

Finally you get Velvet Bean and nGin™ . Velvet bean is a source of L-DOPA, which is a precursor to dopamine. This can help with reward-motivated behavior, and can help with energy. nGin™ is a ginseng extract that may help with mood and cognition. At 100mg, you are getting a solid dose. 

Cognigen is a nice low-stim option that will make you feel good, and could make you more productive. Morphogen never seems to miss!

Who Makes It?

Morphogen is a brand that is known for their loaded products with impressive profiles. While not widely available, this gives them the option to make some of the best formulated products on the market. With the owner being an industry veteran with plenty of experience and qualifications when it comes to formulations, Morphogen knows how to deliver loaded, yet fun products that are almost too goo for their own good sometimes. There is no Morphogen product that disappoints as far as we know. 

GHOST Gamer is the product on this list, and it could very well be number one on this list as well, and is currently #1 on another list. GHOST Gamer is a nootropic targeted towards Gamers, as it is a fast growing category in our space it seems. To start, we have to say that GHOST Gamer is easily the best flavored product on this list. Of course, taste is subjective, and some people say cucumbers taste better pickled, but here on FI, we can safely say that Gamer is a great tasting supplement, and easily #1 for that reason on this list. 

Of course flavor isn't the only reason GHOST Gamer is on this list. Gamer is a very well formulated product, that provides subtle energy that puts you in a prime state of mind to play video games at your fullest capability. The profile starts off with an ingredient that is new to the market, and is meant for gaming. NooLVL® is an ingredient from Nutrition21®, and has been studied on Gamers. Be sure to check out our video on NooLVL for more info. Either way, you are getting 1.6 grams of NooLVL in Gamer, which is the clinical dose. Following this you get 1 gram of Taurine, which helps can help with hydration, blood flow, and cognitive function as well. 

Tyrosine is in here and for good reason, as it helps with focus under stressful situations, which happens a lot when you're playing some video games. At 1 gram it is dosed well. You also get 500mg of Cognizin®, which is Citicholine. This is a high quality form of Choline, and is perfect for Gamer. Rounding this out you get 150mg of Caffeine, 40mg of Theobromine, and AstraGin®. The amount of Caffeine is great, as it is enough to boost focus and energy without making you jittery. 300mg of Caffeine and sitting around isn't the best way to go. AstraGin is great for absorption, and is dosed well. 

Overall, Gamer is the best nootropic for gaming, and it can be used for being productive as well. Most people who buy it tend to use it for working out, productivity, and much more than just gaming, and with such great flavors, this is one you will most likely stock up on... we certainly have. 

Who Makes It?

GHOST is a fully transparent brand in the supplement industry. They are more than a supplement brand, they are a lifestyle (that's really what they are going for). They could easily attract consumers with their amazing YouTube Channel and marketing campaigns, which they do, but they keep them with their quality formulas and products.

Core ZONE continues to stick in our top five, and for good reason. It is a very versatile nootropic supplement that can be used for al most any situation. We here on Fitness Informant loved it for how productive it made us. We hate to say it, but it really put us... "in the Zone".

The profile is very straight forward, and besides the Pregnenolone, uses nothing we haven't sen in a nootropic before. With that said, everything is dosed well, and it all comes together to deliver an awesome experience. With that said, the profile starts off with two well known nootropic ingredients, ALCAR and Tyrosine. Both are staples in many nootropics and pre-workouts, and at a gram each, they are dosed well. You also get 500mg of Citicholine, which converts to Acetylcholine in the brain, a neurotransmitter. 

Bacopa and Mucuna are also in here, both dosed well and have multiple benefits. Mucuna is a source of L-Dopa, which is a precursor to Dopamine. You also get a solid dose of Caffeine at 150mg, which is a great spot for a nootropic, as it isn't overpowering however it should provide a solid boost in energy.

Zone also contains Neurofactor® and Pregneolone. Neurofactor® is great for brain health, and is at 100mg, the clinical dose. Pregnenolone is a neurosteroid and Core is one of the first few brands to actually use this, as you see it in their pre-workout as well. 

Overall, Zone is simply a great Nootropic, and works for just about any situation. It really is great for when you want to get work done, however even when stacked with a pump product makes for a great pre-workout. This is certainly a nootropic worth grabbing.

Who Makes It?

Core Nutritionals is a brand from Doug Miller. It has been around for a long time now, and has certainly stood the test of time. They are known for making some of the best formulas on the market and never seem to disappoint when it comes to new product or flavor launches.

Neuro 365 is awesome for its convenience and the fact that it is a non-stimulant nootropic. Glaxon does a great job of putting emphasis on science in their products, and Neuro 365 is no exception to that rule

As a society we consume so much caffeine and energy drinks, it is refreshing to have Neuro 365 as an option. This is a great add-on nootropic to other stim based products, or even used as a standalone option.

We love the use of Lion's Mane at 500mg combined with 50mg Neurofactor, Bacognize and Rhodiola. This will definitely be a mind clarity and focus application that works (spoiler: it does). 

Another really cool aspect about Neuro 365 is not only does it improve clarity and focus, it can elevate mood. The LTP Factors section of the supplement facts panel is dedicated to improving overall mood and energy which goes hand-in-hand with focus improvement.

Glaxon also adds in Lipidox to aid with absorption to make sure you're actually getting the ingredients to where they need to go. 

Overall, this is going to be one of the best capsule nootropics on the market today.

Who Makes It?

Glaxon is a science-first brand that really focuses on bringing innovation to the category. They are also very good at marketing. The combination of formulas/science and branding really catapulted Glaxon into one of the faster growing brands in the space with amazing products.