The 5 Best Fat Burner Supplements In 2025: Our Tested Reviews

GHOST Burn was our Top Rated fat burner for the year of 2019,  and it has certainly already made a name for itself. Great marketing aside, Ghost knows how to formulate effective products. Ghost Burn is somehow still #1. It is crazy to see a product be on top this long, so kudos to GHOST for that. In this cool looking tub, we get a transparent profile with some very solid ingredients. To start, you get 3 grams of Carnitine… more specifically, 1.5 grams of Acetyl-L-Carnitine, and 1.5 grams of L-Carnitine Tartrate. ALCAR has nootropic benefits, and is our favorite form of Carnitine.

Along with this solid dose of Carnitine, you get a clinical dose of KSM-66. KSM-66 is  Ashwagandha, which is great for stress. Decreasing stress is  a great way to help with fat loss. Some people overdo it when it comes to stimulants. While stimulants can certainly help with fat loss, they do increase cortisol as a side effect. Excess cortisol can hinder fat loss, therefore having an ingredient to counteract this is great to see in a fat burner.

GHOST Burn also contains MitoBurn, which is the newest addition to the formula. It is a source of L-BAIBA, which is an amino acid you body releases when you exercise. They did get rid of Grains of Paradise, which was in the older formulas. Most likely due to the spiciness it gave older Burn formulas.

Where Ghost Burn shines is in the nootropic department. With L-Tyrosine, ALCAR, Choline Bitartrate, and Neurofactor™, this is one of the top supplements for flat out focus, as far as fat burners go that is. So much so, that our user started using as a pre-workout. Overall, it’s a product you can tell had effectiveness in mind, and that’s what we like to see most here on FI. 

Who Makes It?

GHOST is a fully transparent brand in the supplement industry. They are more than a supplement brand, they are a lifestyle (that's really what they are going for). They could easily attract consumers with their amazing YouTube Channel and marketing campaigns, which they do, but they keep them with their quality formulas and products.

Thermo 212 is a hard hitting powdered thermogenic from Axe & Sledge that quickly became one of our favorites here on FI. The brand has certainly upped their products lately, and this one hits hard. The profile contains a nice blend of ingredients that are not only going to give you energy and focus, but also make you sweat!

The profile contains 2 forms of Carnitine, in both ALCAR and L-Carnitine Tartrate form. Acetyl-L-Carnitine is our favorite form of Carnitine, and at 1.5 grams it is certainly a nice addition. Along with the gram of Tyrosine and 300mg of Caffeine, you are certainly going to get a nice boost in energy and focus in 212 Thermo.

Of course this is not just a nootropic/stim-bomb. You also get some ingredients that can help with fat loss through other pathways. You also get InnoSlim, which is a non-stimulant ingredient that helps with fat loss by increasing Adiponectin levels and increasing AMPK. You also get CaloriBURN, which is a trademarked form of Grains of Paradise. This can activate brown adipose tissue, and has some other benefits as well. 

You also get Bitter Orange Extract which acts as a mild beta-agonist, as well as Black Pepper Extract which may aid in absorption. You also get 40mg of ProGBB. 

So the profile is great, but what we really love is the experience. You get a strong boost in energy and focus, but with the added GBB and CaloriBURN, you get a nice boost in thermogenesis and sweat. We are huge fans of GBB here on FI, mainly because it is something that makes you “feel” something. The sweating from Thermo 212 is on par with every other product on this list, and since that is something many look for in a fat burner, we have to give it props. You certainly get appetite suppression, thermogenesis, and energy from 212 Thermo, which makes it one of our top fat burners.

While the flavor might have a slight spice to it for some, 212 Thermo comes in 2 great flavors (so far). Passion Melon Punch, and Spicy Mango. We highly suggest the Spicy Mango!

If you want a great tasting, well dosed thermogenic powder with good flavoring, Thermo 212 is an easy option. 

Who Makes It?

Axe & Sledge is a fast-growing brand that was founded by Seth Feroce. With “hard-work” and “blue-collar” branding, it certainly has the formulas to match. With great products and a great team behind the brand, they are certainly a brand to add to your “must-try” list.

Morphogen Nutrition is one of our favorite lines here on FI. For the longest time, they were always known as the brand that makes products that are almost overloaded and perhaps even “too much”. With that said, we have to give them credit where credit is due, and this is one product that went through a reformulation, and is still top of the line.

Thermogen is a thermogenic powder meant to be taken pre-cardio. The profile starts off with 2g of Tyrosine, which is a common ingredient in fat burners, pre-workouts, and nootropics. It is a precursor to Dopamine, and helps with focus under stressful situations. It is also important for thyroid function. 2g is a solid dose. Acetyl-L-Carnitine (ALCAR) is the next ingredient in Thermogen. ALCAR is our favorite form of Carnitine, and we like seeing it in just about any formula. Carnitine is important as it helps your body transport fat to be used as energy. We like ALCAR the most as it has nootropic benefits, so not only may it help with fat loss, but also help you stay sharp. Choline Bitartrate is the next ingredient, and it is another popular nootropic ingredient. Choline converts to Acetylcholine in the brain, which is a neurotransmitter. 

Now we have our first botanical in Thermogen. Yerba Mate is something you have probably seen at health stores in drinks, or have at least have heard of, as it is a source of Caffeine. You get 500mg of it in here, and it helps with appetite suppression, and has antioxidant properties. This is followed by English Ivy, which can act as a mild Beta-Agonist. This may help with breathing, as well as energy. 

Now we come to our second source of Caffeine, which is Infinergy®. This is a time-released Caffeine, meaning it is released over time, which helps prevent crashes and may be easier on the stomach. You get 275mg of Infinergy® in here, which gets you just barely over 200mg of Caffeine. After this you get another Beta-Agonist in the form of Synephrine coming from Bitter Orange extract. Synephrine is a mild Beta-Agonist, and is greta when paired with Caffeine. You get a solid dose in here at 175mg.

Finally you get Alpha Yohimbine and GBB. GBB helps with Carnitine levels in the body, and has this fun side effect that just makes you sweat. You can be driving to work minding your own business and suddenly have beads of sweat dripping down. 50mg is a strong dose, and some love it, others hate it. Alpha Yohimbine is an Alpha-Agonist, which helps with fat burning. This one can cause some anxiety in people, sso start with a half serving.

Morphogen Thermogen is a solid fat burner that makes for a solid pre-cardio option. It will certainly have you feeling energized, help you burn more calories, make you sweat, and suppress your appetite.

Who Makes It?

Morphogen is a brand that is known for their loaded products with impressive profiles. While not widely available, this gives them the option to make some of the best formulated products on the market. With the owner being an industry veteran with plenty of experience and qualifications when it comes to formulations, Morphogen knows how to deliver loaded, yet fun products that are almost too goo for their own good sometimes. There is no Morphogen product that disappoints as far as we know. 

Apollon really does infest our lists, and we don’t mean that in a bad way! You can always count on Apollon to make something that is among the best when it comes to formulas, and this one is no different. Here we have Molotov V3, a non-stim capsule-based fat burner, that can be taken anytime of the day. 

The profile starts off with MitoBurn, which is a source of L-BAIBA. This has health benefits, and is actually something your body releases when you workout. Following this comes Dandelion, which is a natural diuretic. You get 500mg of Dandelion in Molotov V3. 

Next up is CalorieBurn GP, which is a source of 6-Paradol. This is a quality form of Grains of Paradise, which may aid with fat loss. At 250mg, you are getting a solid dose. Another non-stim ingredient is InnoSlim. This is an ingredient from NuLiv Science that is a blend of Panax notoginseng and Astragalus membranaceus. It can activate AMPK, and promote glucose uptake. At 250mg, you are getting the clinical dose. 

Finally we have Capsimax and GBB. Capsimax is a source of Capsaicin, which can help with thermogenesis. At 100mg, the dose is good! As for GBB, it helps with Carnitine production, and has this fun side effect. That side effect is SWEAT. GBB can make you sweat even if you are not doing anything active. At 60mg, you are getting a strong dose. 

This is a non-stim option in a capsule form, and making is a solid option for nighttime, as well as anytime throughout the day. It can be stacked with most stim-based fat burners, and we like to add this to our pre-workouts when we cut to give us an edge.

Who Makes It?

Apollon Nutrition is a hardcore supplement line that isn't afraid to go places other brands haven't. Not only are they hardcore, they know how to make great products and care about providing clinical doses of ingredients. Certainly not a brand for beginners, however seasoned veterans and supplement nerds will certainly be impressed with what they do.

Now when many people think of fat burners, they think of stim-laden capsules or powders that will make them sweat and feel jittery. Well Apollon, who is known for having several stim-bomb pre-workouts, has actually gone out of their way to show you that you can burn fat while you sleep. This is not a simple stim-free fat burner, this is a well-formulated sleep aid with added non-stim based ingredients that have been shown to help burn fat. 

Night Night Fatty starts off with Glycine, which is an inhibitory neurotransmitter, and we are seeing this more and more in sleep aids. It is at 3g, which is a hefty dose. Following this you get another inhibitory neurotransmitter, and probably the most well-known one… GABA. This comes in at 3g, which is another strong dose. 

Next up come Carnitine Tartrate. This is a good source of Carnitine, which helps your body transport fatty acids to be used as energy. Now we come to an interesting one. Zylaria®  is a mushroom from Xylaria nigripes, and it helps your body create more GABA from within. At 1.5g, it is well above the usual 500mg you see in other products. 

Lemon Balm is a somewhat popular herb that people use to help with calmness, and at 1g is dosed double than what you typically see. Now we have our first true “fat burning” ingredient MitoBurn™. This is a source of L-BAIBA, which is an amino acid that your body releases when you exercise, and has some potential health benefits. A full gram is great to see

Next we have Theanine and Ornithine. Theanine is in everything these days, from pre-workouts, to nootropics, and sleep aids. It can help with calming, and 500mg in here is quite a solid amount. As for the Ornithine HCl, it has been shown in a human study to help with sleep, and the study used 400mg, which is what you get in Night Night Fatty.

Now we come to InnoSlim®, which is a blend of Astragalus and Ginseng extracts that may help with a healthy metabolism. Apollon of course uses the clinical dose at 250mg. Sensoril® makes an appearance, and it is a welcome addition. This is a source of Ashwagandha, and is a great source of Withanolides. This can help with overall stress levels, unlike other sources of Ashwagandha, you don’t need high doses due to the strength of the extract. 

AstraGin® makes an appearance in Night Night Fatty, as it may help with absorption of some ingredients. Finally, we have Melatonin, which is by far the most popular ingredient for sleep. Melatonin is a hormone that many use on its own. It has a big effect on your sleep, and some people love it or hate it. You get 5mg in Night Night fatty, which is on the higher side. Some may experience a sleep hangover from this dose, so we recommend trying a half serving your first time!

In true Apollon fashion, they somehow made a sleep aid hardcore… which is no surprise to us at this point. If you are on a cut, this may be a great way to get better sleep, which is important for weight management, and have some extra ingredients to help with overall fat loss.

Who Makes It?

Apollon Nutrition is a hardcore supplement line that isn't afraid to go places other brands haven't. Not only are they hardcore, they know how to make great products and care about providing clinical doses of ingredients. Certainly not a brand for beginners, however seasoned veterans and supplement nerds will certainly be impressed with what they do.